I've tried multiple times to get rid of the Win32TrojanTdss malware using Ad-Aware, but have not had any success. In fact, it's gotten worse since I've tried. At this point, I can't run Ad-Aware, can't get any web browsers to work (Firefox, Chrome, IE), and get a bunch of unprompted "your computer is infected" type pop-ups, including hijacking my background.

If I start in Safe Mode, I am able to run Ad-Aware, but it doesn't solve the problem.

I would normally post my Ad-Aware scan log, but I can't get online from my computer to post it (I'm on another computer now).

I will try to get my log posted while I wait for any response/suggestion on how to start getting rid of this virus. Thanks.

EDIT: I am now able to get online using my infected computer, but when I try to open my scan log, I get the pop-up quote-box from my system tray saying "WARNING! Application cannot be executed. The file notepad.exe is infected. Please activate your antivirus software."

There is also a "System Security Warning" that keeps popping up, with a black and gold striped shield icon. I am not sure if this is real or not, but I've never seen it before, so I assume it's part of the spyware/malware.

Looks like you need help from the experts in the HijackThis forum (links in my signature). It may be tough without an internet connection, you may need to download programs and install them from a usb stick. Some malware prevents HijackThis from running - if so, try renaming the .exe. Once you get a HijackThis log, open a new thread in that forum and copy/paste or link to this thread to describe the problem, and somebody there can help you with malware removal.